NIMR Researchers Uncover Hidden Threats in Food and COVID-19 Co-Infections

• COVID-19 & Bacterial Co-Infection: Researchers found that Klebsiella pneumoniae infections mimicked COVID-19 symptoms, complicating diagnosis and treatment. Some strains were antibiotic-resistant.
• Food Safety Risks in Lagos: An ongoing study in slum and non-slum areas is assessing vended food, food handlers, and environmental factors linked to outbreaks of cholera and typhoid.
• Health Policy Impact: Findings from these studies could influence public health measures, improving food safety regulations and infectious disease management in Lagos State.

A team of researchers from the MB and BT departments has made significant discoveries regarding the role of Klebsiella pneumoniae in COVID-19 symptomatology and the safety of vended food in Lagos State.

Their findings could reshape public health policies on infectious disease management and food safety.

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During the COVID-19 pandemic, the research team identified cases where patients who tested negative for the virus still displayed COVID-like symptoms. Further investigations revealed that some of these individuals were actually infected with Klebsiella pneumoniae, a bacterial pathogen known to cause respiratory infections.

Additionally, some COVID-19-positive patients were found to have co-infections with the bacteria, complicating treatment. More concerning was the discovery that certain strains of Klebsiella pneumoniae carried antibiotic-resistant genes, making them harder to treat. These findings were presented at an international conference in Paris in 2024.

 

The team also examined the role of Staphylococcus aureus as a co-infection with SARS-CoV-2, with their study now published in scientific journals. Furthermore, they explored variations in ACE-2 receptors, which may influence how susceptible individuals are to COVID-19.

Beyond infectious diseases, the researchers turned their attention to food safety, particularly in slum and non-slum communities of Lagos. In an ongoing study across Alimosho, Oshodi-Isolo, Surulere, Ikorodu, and Lagos Mainland, the team is analyzing vended food samples, food handlers, and environmental factors contributing to enteric infections such as cholera and typhoid.

 

Speaking on the rationale behind the study, a lead researcher stated, “Slum areas are frequently hit by outbreaks, and these infections can easily spread to non-slum communities. By understanding the risks in food handling and hygiene, we can take steps to prevent disease transmission.”

 

The study, which involves collaboration with Health District IV officials, aims to strengthen food safety policies and improve public health awareness. Advocacy efforts have already begun, with food handlers receiving training at the Nigerian Institute of Medical Research (NIMR).

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The research findings are expected to benefit Lagos residents by providing scientific evidence to guide food safety regulations and disease control strategies.

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