US health authorities on Tuesday recommended pausing the Johnson & Johnson Covid shot over blood clot fears, with the company quickly announcing it would delay its European rollout, in a setback for global immunization campaigns.
Out of nearly seven million Americans who have so far received the single dose vaccine, six women aged between 18 and 48 developed a rare type of clot in the brain along with low platelets, officials said.
One later died while another is in critical condition.
Food and Drug Administration scientist Peter Marks said the disorder might be triggered by a rare immune response to the vaccine similar to that seen among a few hundred recipients of the AstraZeneca jab in Europe.
Both vaccines are based on adenovirus vector technology.
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“We have made the decision to proactively delay the rollout of our vaccine in Europe,” J&J said, in a fresh blow for the hard-hit continent which passed the threshold of one million coronavirus deaths.
The European Union has signed a deal for 200 million shots of the vaccine with an option for 200 million more.
US authorities are now carrying out an investigation which could end up leading to tough regulatory choices, such as restricting the J&J shot to subsets of the population.
People who have received a J&J shot within the past three weeks were asked to report to their doctors if they experienced severe headaches, abdominal pain, leg pain, or shortness of breath.
But the White House said it was confident there would be no “significant impact” on the vaccination plan in the world’s hardest-hit country, where almost half of all adults have now received at least one dose.
Jeff Zients, President Joe Biden’s Covid-19 response coordinator, said that a huge surplus in the supply of two other vaccines — Pfizer and Moderna — meant the country could easily take up the slack.
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